John J. Matulis, SmithKline Beecham Pharmaceuticals, Senior Scientific Analyst/Programmer


Human Genome Data

SB has access to the largest collection of genomic data -- DNA sequences, protein sequences, etc. This data has never been available anywhere before, and SCC is devising ways to get as much useful and important information from it as possible. Thus we have invented novel measures of the quality of the data, new quantitative attributes, and are implementing ways to extrapolate future behaviors of the experiments generating the data. The data are still incomplete, but more is obtained weekly as DNA gets further sequenced in the labs.

Some of these ideas were conceived during our probabilistic simulations of genomic sampling, where we assumed various distributions of outcomes for the genome experiments then experimented with and analyzed the inputs and outputs.


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