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Mathematical and Computational Biology: Computational Morphogenesis, Hierarchical Complexity, and Digital Evolution
Edited by: Chrystopher L. Nehaniv, University of Hertfordshire, Hatfield, UK

Lectures on Mathematics in the Life Sciences
1999; 201 pp; softcover
Volume: 26
ISBN-10: 0-8218-0941-5
ISBN-13: 978-0-8218-0941-9
List Price: US$72
Member Price: US$57.60
Order Code: LLSCI/26
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This volume contains 13 selected lectures from the International Workshop on Mathematical and Computational Biology subtitled "Computational Morphogenesis, Hierarchical Complexity and Digital Evolution" held at the University of Aizu (Japan). This interdisciplinary workshop brought together researchers working on aspects of evolutionary, mathematical, and computational biology that are of particular interest for computer scientists, biologists, and mathematicians. Discussion topics include mathematical approaches for addressing evolutionary problems (such as replication, multicellularity, individuality, and morphogenesis), the theoretical tools for rigorously developing these questions, software systems and applications.

Of special concern were self-replication, the evolution of individuality, symbiogenesis, evolutionary developmental biology, computational morphogenesis, interaction dynamics, the evolution and maintenance of sex, and properties of the digital genetic code. Lectures are organized roughly according to increase of biological scale in the order of themes presented at the workshop.


Graduate students and research mathematicians working in mathematical biology; computer scientists; biologists.

Table of Contents

  • E. Szathmáry -- Chemes, genes, memes: A revised classification of replicators
  • J. D. Lohn -- Cellular space models of self-replicating systems
  • L. Bull -- On the evolution of eukaryotes: Computational models of symbiogenesis and multicellularity
  • R. E. Michod and D. Roze -- Cooperation and conflict in the evolution of individuality. III: Transitions in the unit of fitness
  • C. L. Nehaniv and J. L. Rhodes -- On the manner in which biological complexity may grow
  • T. Unemi -- A simple evolvable development system in Euclidean space
  • V. V. Savchenko, A. G. Basnakian, and A. A. Pasko -- Computer simulation and analysis of a growing mammalian cell colony
  • J. R. Peck, J. M. Yearsley, and D. Waxman -- Why do asexual and self-fertilising populations tend to occur in marginal environments?
  • K. Sigmund -- The social life of automata
  • L. M. Schmitt and C. L. Nehaniv -- The linear geometry of genetic operators with applications to the analysis of genetic drift and genetic algorithms using tournament selection
  • S. Okuyama -- Evolution of diseases
  • G. Pirillo -- Maximal circular codes and applications to theoretical biology
  • Q.-P. Gu, S. Peng, and Q.-M. Chen -- Sorting permutations and its application in genome analysis
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