Abstract
In [4], a diffusion model is constructed for a genetic system in which all alleles are selectively neutral and all mutants are new. The state of this model is the vector of order statistics of the gene frequencies. This reordering of the frequencies is necessary because of the assumption on mutation. Fixing the order of the alleles results in a model in which the sum of the gene frequencies is less than one for all positive time. Unfortunately, reordering makes it virtually impossible to study models with selection using this approach.
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Ethier, S.N., Kurtz, T.G. (1987). The Infinitely-Many-Alleles Model with Selection as a Measure-Valued Diffusion. In: Kimura, M., Kallianpur, G., Hida, T. (eds) Stochastic Methods in Biology. Lecture Notes in Biomathematics, vol 70. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-46599-4_6
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DOI: https://doi.org/10.1007/978-3-642-46599-4_6
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