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Quarterly of Applied Mathematics

Quarterly of Applied Mathematics

Online ISSN 1552-4485; Print ISSN 0033-569X

   
 
 

 

Mathematical modelling of avascular ellipsoidal tumour growth


Authors: G. Dassios, F. Kariotou, M. N. Tsampas and B. D. Sleeman
Journal: Quart. Appl. Math. 70 (2012), 1-24
MSC (2010): Primary 92C05, 92C50
DOI: https://doi.org/10.1090/S0033-569X-2011-01240-2
Published electronically: September 15, 2011
MathSciNet review: 2920612
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Abstract | References | Similar Articles | Additional Information

Abstract: Breast cancer is the most frequently diagnosed cancer in women. From mammography, Magnetic Resonance Imaging (MRI), and ultrasonography, it is well documented that breast tumours are often ellipsoidal in shape. The World Health Organisation (WHO) has established a criteria based on tumour volume change for classifying response to therapy. Typically the volume of the tumour is measured on the hypothesis that growth is ellipsoidal. This is the Calliper method, and it is widely used throughout the world. This paper initiates an analytical study of ellipsoidal tumour growth based on the pioneering mathematical model of Greenspan. Comparisons are made with the more commonly studied spherical mathematical models.


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Additional Information

G. Dassios
Affiliation: Department of Chemical Engineering, University of Patras, GR 265 04, Patras, Greece and ICE-HT/FORTH, Greece
MR Author ID: 54715

F. Kariotou
Affiliation: Department of Chemical Engineering, University of Patras, GR 265 04, Patras, Greece

M. N. Tsampas
Affiliation: Department of Chemical Engineering, University of Patras, GR 265 04, Patras, Greece

B. D. Sleeman
Affiliation: School of Mathematics, University of Leeds, Leeds, LS2 9JT, United Kingdom

Received by editor(s): March 18, 2010
Published electronically: September 15, 2011
Article copyright: © Copyright 2011 Brown University